Johns Hopkins Medicine scientists say they have shed new light on how bacteria protect themselves from certain phage invaders 鈥� by seizing genetic material from weakened, dormant phages and using it to 鈥渧accinate鈥� themselves to elicit an immune response.
In a groundbreaking study on the synthesis of cellulose 鈥� a major constituent of all plant cell walls 鈥� a team of Rutgers University-New Brunswick researchers has captured images of the microscopic process of cell-wall building continuously over 24 hours with living plant cells, providing critical insights that may lead to the development of more robust plants for increased food and lower-cost biofuels production.
Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.
Aging compromises the lymphatic vessels surrounding the brain, disabling waste drainage from the brain and impacting cognitive function. Researchers at WashU Medicine boosted lymphatic vessel integrity in old mice and found improvements in their memory compared with old mice without rejuvenated lymphatic vessels.
Tiny nematodes, commonly known as vinegar eelworms, can move objects with a force hundreds of times their own weight.
New research from UChicago upends traditional views on how synaptic plasticity supports memory and learning.
Researchers at UC San Diego have confirmed the presence of xylazine in the illicit drug supply at the U.S.-Mexico border. While xylazine remains less common in the Western U.S., border cities serve as key trafficking hubs and may have higher rates of emerging substances.
Find how a mitochondrial protein protects cancer cells from immunotherapy, giving scientists a new target type to improve solid tumor treatment & save lives.
An experimental drug appears to reduce the risk of Alzheimer鈥檚-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a study led by the Knight Family Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), which is based at WashU Medicine.
Scientists at Washington University School of Medicine in St. Louis and the Perelman School of Medicine at the University of Pennsylvania have identified a key component to launching immune activity 鈥� and overactivity. The researchers identified a protein in cells that spurs the release of infection-fighting molecules. The protein, whose role in the immune system had not previously been suspected, provides a potential target for therapies that could prevent overreactive immune responses that are at the root of several debilitating illnesses.
Iowa State researchers are combining bio-based reactions with electricity-driven reactions as a potential step toward transforming chemical manufacturing to a greener industry that鈥檚 less dependent on petroleum-based materials and the need to process them with high energies, temperatures and emissions.
Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. Published in npj Breast Cancer, the study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.
A new large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients.
A grant to Wayne State University from the National Science Foundation (NSF) is opening new doors for researchers and students to explore the future of autonomous vehicles, machines and drones. Zheng Dong, Ph.D., assistant professor of computer science in Wayne State鈥檚 School of Engineering, was awarded a five-year, $595,611 NSF grant for the project, "CAREER: ChronosDrive: Ensuring Timing Correctness in DNN-Driven Autonomous Vehicles with Accelerator-Enhanced Real-Time SoC Integration."
Adding an anti-obesity medication just one month after behavioral therapy begins鈥攔ather than waiting the currently recommended six months鈥攃an more than double weight loss for patients who struggle initially with lifestyle changes alone, according to new research published in Nature Medicine from a team at the Perelman School of Medicine at the University of Pennsylvania.
Research by Frances Kraus, Jason Parisi and Willca Villafana will be featured in the Physics of Plasmas Early Career Collection.
Existing antivirals may be less effective against this H5N1 bird flu strain, and prevention measures, such as avoiding raw milk consumption and reducing exposure in dairy workers, may be the most effective way to protect against the virus.
Physician-scientist Theodore Scott Nowicki, MD, PhD, an assistant professor-in-residence of pediatric hematology/oncology and microbiology, immunology, & molecular genetics at the David Geffen School of Medicine at UCLA, has been awarded a $4.5 million R37 MERIT Award to help improve the effectiveness of cellular therapies for solid tumors.
A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.
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A new study led by Dr. Roy Herbst, deputy director of Yale Cancer Center, found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer, years after their treatment.
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