• share
• favorite_border

Johns Hopkins Medicine scientists say they have shed new light on how bacteria protect themselves from certain phage invaders 鈥� by seizing genetic material from weakened, dormant phages and using it to 鈥渧accinate鈥� themselves to elicit an immune response.

• share
• favorite_border

Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.

• share
• favorite_border

Aging compromises the lymphatic vessels surrounding the brain, disabling waste drainage from the brain and impacting cognitive function. Researchers at WashU Medicine boosted lymphatic vessel integrity in old mice and found improvements in their memory compared with old mice without rejuvenated lymphatic vessels.

• share
• favorite_border

A novel oral combination drug therapy evaluated at Huntsman Cancer Institute could treat and prevent melanoma spreading to the brain. Brain metastasis is the main cause of death from melanoma.

• share
• favorite_border

Scientists at Washington University School of Medicine in St. Louis and the Perelman School of Medicine at the University of Pennsylvania have identified a key component to launching immune activity 鈥� and overactivity. The researchers identified a protein in cells that spurs the release of infection-fighting molecules. The protein, whose role in the immune system had not previously been suspected, provides a potential target for therapies that could prevent overreactive immune responses that are at the root of several debilitating illnesses.

• share
• favorite_border

By assessing how 鈥渟ticky鈥� tumor cells are, UC San Diego researchers have found a potential way to predict whether a patient鈥檚 early-stage breast cancer is likely to spread. The discovery could help doctors identify high-risk patients and tailor their treatments accordingly.

• share
• favorite_border

Protein crystallization at the SER-CAT beamline at Argonne鈥檚 Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.

• share
• favorite_border

Researchers at UChicago, Argonne, and Harvard perfected a new technique for creating experimental movies of proteins in action.

• share
• favorite_border

• share
• favorite_border

鈥� A study from IRB Barcelona, funded by Fundaci贸n CRIS contra el c谩ncer demonstrates that the 鈥減revious state鈥� of blood stem cells plays a decisive role in the subtype of leukaemia that develops. 鈥� The new technique, called STRACK, allows monitoring of the evolution of each cell before and after acquiring oncogenic mutations.

• share
• favorite_border

Johns Hopkins researchers say they found that infection with a common virus that can be transmitted from mother to fetus before birth significantly worsens an often-fatal complication of premature birth called necrotizing enterocolitis (NEC) in experiments with mice.

• share
• favorite_border

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

• share
• favorite_border

Scientists uncover an enzyme that boosts cancer cell metabolism to fuel growth

• share
• favorite_border

• share
• favorite_border

Building off previous groundbreaking research, a new study identifies genetic variants that have significant impacts on brain development and are shared across eight different psychiatric disorders.

• share
• favorite_border

Scientists have discovered a configuration of electrical synapses that 鈥渇ilter鈥� sensory information to guide perception and behavior in animals.

• share
• favorite_border

A new machine learning technique could help inform clinical decision-making across hospital systems to address the challenges of long COVID-19 care.

• share
• favorite_border

A new study by researchers at the UNC Thurston Arthritis Research Center at the UNC School of Medicine has identified 13 risk genes that can increase chances for developing osteoarthritis, jumpstarting research that could lead to new, targeted treatments.