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EXPLORER Total Body PET Scanner Helps Detect Brain Disease

UC Davis Health — Wed, 23 Apr 2025 19:05:59 EST

EXPLORER total body PET scanner is creating a new way to visualize the protective barrier to the brain to reveal impacts from cancer and other diseases.

For Eye Infections, Delayed Doctor Visits and Extent of Damage Affect Vision Outcomes

Michigan Medicine - University of Michigan — Wed, 23 Apr 2025 18:35:45 EST

In a study published in Ophthalmology, physicians followed 562 patients in the United States and India over a three-month period to identify risk factors that could be easily managed with early intervention.

LifeArc Joins Transatlantic Collaboration to Develop a Treatment for Crimean-Congo Hemorrhagic Fever

U.S. Army Medical Research Institute of Infectious Diseases — Wed, 23 Apr 2025 18:30:01 EST

A new transatlantic collaboration between the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) and LifeArc will look to develop an affordable and accessible monoclonal antibody therapeutic for Crimean-Congo Hemorrhagic Fever Virus (CCHFV), which could treat and protect thousands of people globally.

Childhood Exposure to Bacterial Toxin May Be Triggering Colorectal Cancer Epidemic Among the Young

University of California San Diego — Wed, 23 Apr 2025 11:00:00 EST

An international team led by the University of California San Diego has identified a potential microbial culprit behind the alarming rise in early-onset colorectal cancer: a bacterial toxin called colibactin.

Parts of Our DNA May Evolve Much Faster than Previously Thought

University of Utah Health — Wed, 23 Apr 2025 11:00:00 EST

A team of researchers has used advanced DNA sequencing to develop the most comprehensive atlas yet of genetic change through generations, laying the foundations for new insights into the roots of human disease and evolution.

Researchers Use Nanoparticles to Target Glioblastoma in Mice

Michigan Medicine - University of Michigan — Wed, 23 Apr 2025 08:00:25 EST

In a study, University of Michigan researchers have created nanodiscs that can target cholesterol levels in GBM, starving the cancer cells and increasing survival rates of the treated mice.

Children Face Elevated Kidney, Heart, and Gut Risks for Years After COVID Infection

Perelman School of Medicine at the University of Pennsylvania — Tue, 22 Apr 2025 18:05:53 EST

Findings included elevated risks for chronic organ disease among children, and revealed some racial differences in long COVID risks

Telemedicine Had an Impact on Carbon Emissions Equivalent to Reducing Up to 130,000 Car Trips Each Month in 2023

University of California, Los Angeles (UCLA), Health Sciences — Tue, 22 Apr 2025 09:00:00 EST

Telemedicine use in 2023 reduced monthly carbon dioxide emissions by the equivalent of up to 130,000 gas operated vehicles or recycling up to 4 million trash bags, suggesting it could have a positive effect on climate change

COVID Vaccine Protected Kids From Long COVID

Perelman School of Medicine at the University of Pennsylvania — Tue, 22 Apr 2025 08:45:13 EST

Instead of special protection against long COVID, vaccines kept children and adolescents from developing the condition by blocking COVID-19 infections in the first place

Two Brain Proteins are Key to Preventing Seizures, Research in Flies Suggests

University of Utah Health — Mon, 21 Apr 2025 13:00:00 EST

One in ten people will have a seizure in their life, but treatments remain limited, in part due to incomplete understanding of the brain mechanisms involved. Now, research in fruit flies has uncovered a role for two specific brain proteins that are necessary during brain development to prevent seizures.

Study Suggests Experimental Cancer Drug Could Streamline Standard Tuberculosis Treatment and Prevent Post-TB Lung Disease

Johns Hopkins Medicine — Mon, 21 Apr 2025 08:00:56 EST

An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping infected cells die a gentler death, Johns Hopkins Medicine investigators report.

Scientists Identify Agent of Transformation In Protein Blobs That Morph From Liquid to Solid

Rutgers University-New Brunswick — Fri, 18 Apr 2025 15:00:00 EST

An international research collaboration led by Rutgers University-New Brunswick scientists that examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid. These mysterious droplets, known as biomolecular condensates, solidify when they carry a high proportion of the protein alpha-synuclein, the scientists reported in Science Advances. Clumps of alpha-synuclein are commonly found in the brain cells of people with Parkinson's disease, a neurodegenerative brain disorder.

Study Highlights Gaps in Firearm Suicide Prevention Among Women

Ohio State University — Fri, 18 Apr 2025 11:00:51 EST

At a time of increased gun ownership among women, a new study found just under 4 in 10 women who died by firearm suicide had no documented history of mental or physical health problems, highlighting a need for prevention strategies tailored to at-risk women.

Monell Center Study Identifies GLP-1 Therapies as a Possible Treatment for Rare Genetic Disorder Bardet-Biedl Syndrome

Monell Chemical Senses Center — Thu, 17 Apr 2025 20:45:00 EST

Monell Center investigators identified that GLP-1R agonists, a class of drugs currently used to treat type-2 diabetes and obesity, as a promising therapeutic for managing the metabolic complications associated with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments. They used a genetically engineered mouse model of BBS that displayed the hallmark features of the condition.

Frequent Use of Antibiotics in Infants and Young Children May Increase Risk for Asthma, Allergies and Other Conditions

Rutgers University-New Brunswick — Wed, 16 Apr 2025 09:20:13 EST

Rutgers Health researchers highlight the connection between early repeated antibiotic use how it impacts the digestive microbiome

Moffitt Study Shows New Immune Boost Could Expand Access to Cancer Immunotherapy

Moffitt Cancer Center — Fri, 11 Apr 2025 10:15:36 EST

Researchers at Moffitt Cancer Center have found that tapping into the body's own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy. Results of their study were published in the Journal for Immunotherapy of Cancer.

Scientists Develop Process Using Molecules in the Cell to Identify Environmental Signals

Rutgers University-New Brunswick — Thu, 10 Apr 2025 20:10:31 EST

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny chemicals relevant to human health. Research by Rutgers University-New Brunswick scientists centers on RNA, a nucleic acid that plays a crucial role in most cellular processes. Their work is expected to have applications in the surveillance of environmental chemicals and, ultimately, the diagnosis of critical diseases including neurological and cardiovascular diseases and cancer.

Researchers Create 'Wiring Diagram' for Key Songbird Brain Region

UT Southwestern Medical Center — Thu, 10 Apr 2025 18:15:06 EST

Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates.

UCLA Researchers Identify Precision Medicine Approach for Preventing Kidney Failure

University of California, Los Angeles (UCLA), Health Sciences — Wed, 09 Apr 2025 14:00:00 EST

UCLA researchers have identified collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, Cilengitide, was found to reduce kidney scarring and slow disease progression in preclinical models, suggesting a possible precision medicine approach for high-risk patients.

A Comprehensive Map of the Human Cell

University of California San Diego — Wed, 09 Apr 2025 11:00:00 EST

By mapping the subcellular architecture of tumor cells, researchers can better understand how mutations cause cancer.

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