New research from the University of Chicago shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own.
In the next steps of the five-year research and education alliance between the Monell Chemical Senses Center and the Singapore Institute of Food and Biotechnology Innovation, a team of scientists from Singapore visited the Monell Center to learn more about Monell science and scientists and plan potential corporate and academic collaborations for the ongoing partnership.
Johns Hopkins Medicine scientists say they have shed new light on how bacteria protect themselves from certain phage invaders 鈥� by seizing genetic material from weakened, dormant phages and using it to 鈥渧accinate鈥� themselves to elicit an immune response.
In a groundbreaking study on the synthesis of cellulose 鈥� a major constituent of all plant cell walls 鈥� a team of Rutgers University-New Brunswick researchers has captured images of the microscopic process of cell-wall building continuously over 24 hours with living plant cells, providing critical insights that may lead to the development of more robust plants for increased food and lower-cost biofuels production.
Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.
A novel oral combination drug therapy evaluated at Huntsman Cancer Institute could treat and prevent melanoma spreading to the brain. Brain metastasis is the main cause of death from melanoma.
Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.
A research team investigates how genome editing can be harnessed to accelerate cassava breeding and improve key traits.
An FFG-funded consortium of Austrian research groups from the University of Vienna, MedUni Vienna and Technikum Wien together with company partner DOC Medikus GmbH has developed an innovative bioanalytical test system for radiopharmaceutical drug candidates for cancer diagnosis and therapy. It does not require any animal testing at all and enables automated, fast and highly precise analyses. The new method was presented in detail in the renowned Journal of Nuclear Medicine.
What happens when cancer doesn鈥檛 respond to chemotherapy? 聽A revolutionary therapy called chimeric antigen receptor (CAR) T-cell therapy uses a person鈥檚 own immune cells that have been modified to recognize and attack cancer cells.
West Virginia University neuroscientists have discovered a way to control how much zinc is released to specific locations in the brain. The essential mineral plays a major role in the organ鈥檚 function, including improving memory and lessening symptoms of some neurological disorders, but getting the right amount to the right place is key.
Researchers at The University of Texas at El Paso have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide. The results of the new study were recently published in the International Journal of Molecular Sciences.
Hearing the word 鈥渓eukemia鈥� can be alarming in any context. Hearing it in the context of your child鈥檚 health might feel terrifying, unfair, and even hopeless.聽But according to leading pediatric leukemia experts, families grappling with the news of a diagnosis have reason to feel .Today, for a great majority of pediatric leukemia cases, a new diagnosis doesn鈥檛 mean what it meant 30, 20, or even 10 years ago.
Nashville Biosciences LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, and global DNA sequencing giant Illumina Inc. today announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative. Insights from the AGD database are being leveraged to accelerate drug target discovery, therapeutic research and clinical development.
An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a first-ever clinical test of the targeted therapy avapritinib in pediatric and young patients with a form of high-grade glioma. They found that the drug, already FDA-approved for certain adult cancers, was generally safe and resulted in tumor reduction visible on brain scans, as well as clinical improvement, in 3 out of 7 patients.
Caris Life Sciences庐 (Caris), a leading next-generation AI TechBio company and precision medicine pioneer, today announced the publication of "Real-world evidence provides clinical insights into tissue-agnostic therapeutic approvals" in Nature Communications.
Find how a mitochondrial protein protects cancer cells from immunotherapy, giving scientists a new target type to improve solid tumor treatment & save lives.
Un descubrimiento realizado por investigadores de Mayo Clinic puede ayudar a explicar por qu茅 la inmunoterapia no ha sido 煤til para muchos pacientes con c谩ncer colorrectal metast谩sico. En los descubrimientos publicados en Clinical Cancer Research, el equipo identific贸 prote铆nas espec铆ficas 鈥� fibronectina y actina del m煤sculo liso 鈥� dentro de los tejidos del c谩ncer colorrectal que est谩n asociadas con la resistencia al tratamiento de inmunoterapia.
Uma descoberta feita por pesquisadores da Mayo Clinic pode ajudar a explicar por que a imunoterapia n茫o tem sido 煤til para muitos pacientes com c芒ncer colorretal metast谩tico. Nas descobertas publicadas na Clinical Cancer Research, a equipe identificou prote铆nas espec铆ficas 鈥� fibronectina e actina do m煤sculo liso 鈥� dentro dos tecidos do c芒ncer colorretal que est茫o associados 脿 resist锚ncia ao tratamento imunoter谩pico.
An experimental drug appears to reduce the risk of Alzheimer鈥檚-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a study led by the Knight Family Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), which is based at WashU Medicine.
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