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Copy Number Variant Analysis Improves Diagnostic Yield in a Diverse Pediatric Exome Sequencing Cohort

Highlight:Exome sequencing (ES) is commonly used to diagnose Mendelian disorders, which occur when pathogenic variant(s) in a gene are either inherited from one or both parents or are de novo. Examples of such disorders include cystic fibrosis and...
2-May-2025 10:55 AM EDT Add to Favorites

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What is Infant Mental Health? Your Questions Answered

We usually think about the mental health of older teens and adults. But what does mental health mean for babies? Marian E. Williams, PhD, Clinical Psychologist and Director of the Stein Tikun Olam Early Connections Program at Children鈥檚 Hospital...
1-May-2025 6:10 PM EDT Add to Favorites

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Children鈥檚 Hospital Los Angeles and leading Middle East Hospital Establish Strategic Collaboration to Benefit Patient Care, Research and Education

Children鈥檚 Hospital Los Angeles announced that it has entered a strategic collaboration with Sidra Medicine, one of the leading hospitals for children and women in Qatar and the Middle East. The Memorandum of Understanding signed by the two...
30-Apr-2025 9:00 AM EDT Add to Favorites

How Organ Shortages Affect the Smallest of Heart Transplant Patients

The ongoing shortage of donor hearts for children who need them stems from multiple causes, including a lack of donor awareness, organ allocation issues, and not enough organs that are of sufficient quality to transplant. Currently, new hearts for...
29-Apr-2025 8:35 PM EDT Add to Favorites

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Children's Hospital Los Angeles Team Is First in World to Investigate Cardiac Xenotransplant as a 鈥楤ridge鈥� for Babies

A team led by Children鈥檚 Hospital Los Angeles has become the first in the world to demonstrate the possibility of using genetically engineered pig hearts as a potential 鈥渂ridge鈥� to heart transplant for critically ill babies. The groundbreaking...
28-Apr-2025 10:45 AM EDT Add to Favorites

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Children's Hospital Los Angeles Celebrates a Dog Therapy Program of the Highest Pedigree

The Amerman Family Foundation Dog Therapy Program at Children's Hospital Los Angeles hosted 鈥淒og Therapy Appreciation Day鈥� celebrating the special connection between CHLA and its therapy dog team.
25-Apr-2025 6:00 PM EDT Add to Favorites

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Children鈥檚 Hospital Los Angeles Launches First-of-its-Kind Sleep App and Sleep Registry for Children Using Apple Watch

Children's Hospital Los Angeles is launching the first sleep registry in the country for children using Apple Watch as well as a new data collection app called WISE-HARE, or Wearable Intelligent Sensor Enhancement Home Apnea Risk Evaluation.
22-Apr-2025 5:55 PM EDT Add to Favorites

Children鈥檚 Hospital Los Angeles Experts to Present at 2025 Pediatric Academic Societies Meeting

Children鈥檚 Hospital Los Angeles experts are set to speak at nearly 80 sessions and poster presentations at the 2025 Pediatric Academic Societies (PAS) meeting April 24-28 in Honolulu.
21-Apr-2025 6:05 PM EDT Add to Favorites


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Recognizing and Overcoming Postpartum Depression

Having a baby is a life-changing experience filled with emotion. It can bring great joy, fulfillment, and a sense of purpose, but also feelings of sadness, irritability, self-doubt, inadequacy, and exhaustion. When the negative feelings begin to...
10-Apr-2025 9:25 AM EDT

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Genome Sequencing Finds Answers to Mystery Conditions in the NICCU

When a critically ill infant is admitted to the Steven & Alexandra Cohen Foundation Newborn and Infant Critical Care Unit (NICCU) at Children鈥檚 Hospital Los Angeles, it can be for an underlying genetic cause for the baby鈥檚 symptoms. The hard...
8-Apr-2025 9:15 AM EDT

Children's Hospital Los Angeles Cardiologist Honored by World Children鈥檚 Transplant Fund

Children鈥檚 Hospital Los Angeles cardiologist Jondavid Menteer, MD, was honored with the World Children鈥檚 Transplant Fund 鈥淲CTF for the Children Award.鈥� The prestigious award recognized Dr. Menteer for 20 years of dedication and leadership in...
24-Sep-2024 11:05 AM EDT

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As FDA Expands Approval of a New Gene Therapy to Treat Duchenne Muscular Dystrophy, a CHLA Expert Weighs in

After previously approving its use for a limited population, the U.S. Food and Drug Administration has now approved Elevidys, a gene therapy designed to treat Duchenne muscular dystrophy (DMD), for a broader range of child patients.
8-Jul-2024 9:05 AM EDT

Children鈥檚 Hospital Los Angeles Neurology Expert Available to Discuss FDA-Approved Gene Therapy Label Expansion for Patients with Duchenne Muscular Dystrophy

20-Jun-2024 9:05 PM EDT

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Pediatric Pulmonologist Leads Translational Research to Treat Chronic Airway Infections in children with Cystic Fibrosis

Dr. Burgener, a pediatric pulmonologist who joined CHLA last summer from Stanford University, studies cystic fibrosis (CF), a genetic disorder that affects the lungs, pancreas and other organs.
15-Apr-2024 9:05 AM EDT

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Medulloblastoma Expert Available

11-Jan-2024 5:05 PM EST

Neonatologist Travels to China to Share ECMO Experience

This spring, Rachel Chapman, MD, traveled to two cities in China to share expertise on one of the most complex lifesaving interventions for critically ill newborns: extracorporeal membrane oxygenation (ECMO).Dr. Chapman, Associate Division Chief of...
3-Aug-2023 7:05 PM EDT

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